| Result | Record | Opponent | Method | Event | Date | Round | Time | Location | Notes |
| Win | 31-8 | Lyoto Machida | Decision (Split) | UFC 123: Rampage vs. Machida | November 20, 2010 | 3 | 5:00 | Auburn Hills, Michigan | |
| Loss | 30-8 | Rashad Evans | Decision (Unanimous) | UFC 114: Rampage vs. Evans | May 29, 2010 | 3 | 5:00 | Las Vegas, NV | #1 contendership for the UFC Light Heavyweight championship |
| Win | 30–7 | Keith Jardine | Decision (Unanimous) | UFC 96: Jackson vs. Jardine | March 7, 2009 | 2 | 3:20 | Columbus, Ohio | Won Fight of the Night |
| Win | 29–7 | Wanderlei Silva | KO (Punch) | UFC 92: The Ultimate 2008 | December 27, 2008 | 1 | 3:21 | Las Vegas, NV | Won Knock Out of the Night |
| Loss | 28–7 | Forrest Griffin | Decision (Unanimous) | UFC 86: Jackson vs. Griffin | July 5, 2008 | 5 | 5:00 | Las Vegas, NV | Lost UFC Light Heavyweight Championship; Fight of the Night; WON Fight of the Year |
| Win | 28–6 | Dan Henderson | Decision (Unanimous) | UFC 75: Champion vs. Champion | September 8, 2007 | 5 | 5:00 | London, England | Defended UFC Light Heavyweight Title, Unified PRIDE Middleweight & UFC Light Heavyweight titles. |
| Win | 27–6 | Chuck Liddell | KO (Punches) | UFC 71: Liddell vs. Jackson | May 26, 2007 | 1 | 1:53 | Las Vegas, NV | Won UFC Light Heavyweight Championship; Won Knock Out of the Night |
| Win | 26–6 | Marvin Eastman | KO (Punches) | UFC 67: All or Nothing | February 3, 2007 | 2 | 3:49 | Las Vegas, NV | UFC Debut |
| Win | 25–6 | Matt Lindland | Decision (Split) | WFA: King of the Streets | July 22, 2006 | 3 | 5:00 | California, US | |
| Win | 24–6 | Dong Sik Yoon | Decision (Unanimous) | PRIDE 31: Dreamers | February 26, 2006 | 3 | 5:00 | Saitama, Japan | |
| Win | 23–6 | Hirotaka Yokoi | TKO (Stomp and Soccer Kick) | PRIDE 30: Fully Loaded | October 23, 2005 | 1 | 4:05 | Saitama, Japan | |
| Loss | 22–6 | Mauricio Rua | TKO (Soccer Kicks) | PRIDE Total Elimination 2005 | April 23, 2005 | 1 | 4:47 | Osaka, Japan | Middleweight Grand Prix Quarter-Final |
| Win | 22–5 | Murilo Rua | Decision (Split) | PRIDE 29: Fists Of Fire | February 20, 2005 | 3 | 5:00 | Saitama, Japan | |
| Loss | 21–5 | Wanderlei Silva | KO (Knees) | PRIDE 28: High Octane | October 31, 2004 | 2 | 3:26 | Saitama, Japan | For Pride Middleweight Championship |
| Win | 21–4 | Ricardo Arona | KO (Slam) | PRIDE Critical Countdown 2004 | June 20, 2004 | 1 | 7:32 | Saitama, Japan | |
| Win | 20–4 | Ikuhisa Minowa | TKO (Knee) | PRIDE Shockwave 2003 | December 31, 2003 | 2 | 1:05 | Saitama, Japan | |
| Loss | 19–4 | Wanderlei Silva | TKO (Knees) | PRIDE Final Conflict 2003 | November 9, 2003 | 1 | 6:28 | Tokyo, Japan | Middleweight Grand Prix Final |
| Win | 19–3 | Chuck Liddell | TKO (Corner Stoppage) | PRIDE Final Conflict 2003 | November 9, 2003 | 2 | 3:10 | Tokyo, Japan | Middleweight Grand Prix Semi-Final |
| Win | 18–3 | Murilo Bustamante | Decision (Split) | PRIDE Total Elimination 2003 | August 10, 2003 | 3 | 5:00 | Saitama, Japan | Middleweight Grand Prix Quarter-Final |
| Win | 17–3 | Mikhail Illoukhine | Submission (Knees) | PRIDE 26: Bad to the Bone | June 8, 2003 | 1 | 6:26 | Yokohama, Japan | |
| Win | 16–3 | Kevin Randleman | KO (Knee and Punches) | PRIDE 25: Body Blow | March 16, 2003 | 1 | 6:58 | Yokohama, Japan | |
| Win | 15–3 | Igor Vovchanchyn | Submission (Injury) | PRIDE 22: Beasts From the East 2 | September 29, 2002 | 1 | 7:17 | Nagoya, Japan | |
| Win | 14–3 | Sean Gray | TKO (Punches) | KOTC 13: Revolution | May 17, 2002 | 3 | 0:37 | Reno, Nevada | |
| Win | 13–3 | Masaaki Satake | TKO (Injury from Slam) | PRIDE 20: Armed & Ready | April 28, 2002 | 1 | 7:07 | Yokohama, Japan | |
| Loss | 12–3 | Daijiro Matsui | DQ (Knee to Groin) | PRIDE 18: Cold Fury 2 | December 23, 2001 | 1 | 0:14 | Fukuoka, Japan | |
| Win | 12–2 | Yuki Ishikawa | KO (Punches) | PRIDE 17: Championship Chaos | November 3, 2001 | 1 | 1:52 | Tokyo, Japan | |
| Win | 11–2 | Alexander Otsuka | TKO (Doctor Stoppage) | BattlArts – BattlArts vs. the World | October 14, 2001 | 2 | 5:00 | Tokyo, Japan | |
| Loss | 10–2 | Kazushi Sakuraba | Submission (Rear Naked Choke) | PRIDE 15: Raging Rumble | July 29, 2001 | 1 | 5:41 | Saitama, Japan | |
| Win | 10–1 | Kenneth Williams | Submission (Rear Naked Choke) | Gladiator Challenge 4 | June 17, 2001 | 1 | 4:40 | California, US | |
| Win | 9–1 | Bryson Howvreck | Submission (Strikes) | KOTC 8: Bombs Away | April 29, 2001 | 1 | 1:48 | California, US | |
| Win | 8–1 | Rocko Henderson | Submission (Kimura) | Gladiator Challenge 3 | April 7, 2001 | 2 | 1:15 | California, US | |
| Win | 7–1 | Dave Taylor | TKO (Towel Thrown Between Rounds) | Gladiator Challenge 2 | February 18, 2001 | 1 | 5:00 | California, US | |
| Win | 6–1 | Charlie West | Decision | Gladiator Challenge 1 | December 9, 2000 | 2 | 5:00 | California, US | |
| Win | 5–1 | Rob Smith | Decision (Unanimous) | KOTC 6: Road Warriors | November 29, 2000 | 2 | 5:00 | Michigan, US | |
| Win | 4–1 | Warren Owsley | Submission (Armbar) | Dangerzone – Night of the Beast | October 28, 2000 | 1 | 6:04 | Virginia, US | |
| Win | 3–1 | Ron Rumpf | TKO (Punches) | CFA 2: Continental Freefighting Alliance 2 | July 19, 2000 | 1 | 1:18 | United States | |
| Loss | 2–1 | Marvin Eastman | Decision (Unanimous) | KOTC 4–Gladiators | June 24, 2000 | 2 | 5:00 | San Jacinto, CA | |
| Win | 2–0 | Marco Bermudaz | Submission (Rear Naked Choke) | HBUP: Huntington Beach Underground Pancrase | May 13, 2000 | 2 | 7:17 | California, US | |
| Win | 1–0 | Mike Pyle | Decision | ISCF – Memphis | November 13, 1999 | N/A | | Tennessee, US | |
