| Result | Record | Opponent | Method | Event | Date | Round | Time | Location | Notes |
| 26–5 | Win | Nate Marquardt | Decision (Unanimous) | UFC 122: Marquardt vs. Okami | 2010-11-13 | 3 | 5:00 | Oberhausen, Germany | Becomes the #1 contender for the UFC Middleweight Championship |
| 25–5 | Win | Mark Muñoz | Decision (Split) | UFC Live: Jones vs. Matyushenko | 2010-08-01 | 3 | 5:00 | San Diego, California, United States | |
| 24–5 | Win | Lucio Linhares | TKO (Doctor Stoppage) | UFC Fight Night: Florian vs. Gomi | 2010-03-31 | 2 | 2:47 | Charlotte, North Carolina, United States | |
| 23–5 | Loss | Chael Sonnen | Decision (Unanimous) | UFC 104: Machida vs Shogun | 2009-10-24 | 3 | 5:00 | Los Angeles, California, United States | |
| 23–4 | Win | Dean Lister | Decision (Unanimous) | UFC 92: Ultimate 2008 | 2008-12-27 | 3 | 5:00 | Las Vegas, Nevada, United States | |
| 22–4 | Win | Evan Tanner | KO (Knee) | UFC 82: Pride of a Champion | 2008-03-01 | 2 | 3:00 | Columbus, Ohio, United States | |
| 21–4 | Win | Jason MacDonald | Decision (Unanimous) | UFC 77: Hostile Territory | 2007-10-20 | 3 | 5:00 | Cincinnati, Ohio, United States | |
| 20–4 | Loss | Rich Franklin | Decision (Unanimous) | UFC 72: Victory | 2007-06-16 | 3 | 5:00 | Belfast, Northern Ireland | To determine a #1 contender for the UFC Middleweight Championship |
| 20–3 | Win | Mike Swick | Decision (Unanimous) | UFC 69: Shootout | 2007-04-07 | 3 | 5:00 | Houston, Texas, United States | |
| 19–3 | Win | Rory Singer | Submission (Punches) | UFC 66: Liddell VS Ortiz | 2006-12-30 | 3 | 4:03 | Las Vegas, Nevada, United States | |
| 18–3 | Win | Kalib Starnes | TKO (Strikes) | UFC 64: Unstoppable | 2006-10-14 | 3 | 1:40 | Las Vegas, Nevada, United States | |
| 17–3 | Win | Alan Belcher | Decision (Unanimous) | UFC 62: Liddell VS Sobral | 2006-08-26 | 3 | 5:00 | Las Vegas, Nevada, United States | UFC Debut |
| 16–3 | Win | Izuru Takeuchi | TKO (Strikes) | GCM: D.O.G. 6 | 2006-06-11 | 1 | 3:39 | Tokyo, Japan | |
| 15–3 | Win | Ji Won Bang | TKO (Strikes) | MARS: World Grand Prix | 2006-05-13 | 1 | 4:38 | Chiba, Japan | |
| 14–3 | Loss | Jake Shields | Decision (Majority) | Rumble On The Rock 9 | 2006-04-21 | 3 | 5:00 | Honolulu, Hawaii, United States | ROTR WW Tournament Second Round |
| 14–2 | Win | Anderson Silva | DQ (Illegal UpKick) | Rumble On The Rock 8 | 2006-01-20 | 1 | 2:33 | Honolulu, Hawaii, United States | ROTR WW Tournament Opening Round. Silva delivered an illegal upkick that rendered Okami unconscious. |
| 13–2 | Win | Myun Joo Lee | TKO (Corner Stoppage) | K-1: Seoul Hero's | 2005-11-05 | 1 | 4:14 | Seoul, South Korea | |
| 12–2 | Win | Damien Riccio | TKO (Strikes) | GCM: D.O.G. 3 | 2005-09-17 | 2 | 2:44 | Tokyo, Japan | |
| 11–2 | Win | Nick Thompson | Submission (Elbow Injury) | GCM: D.O.G. 2 | 2005-06-11 | 1 | 0:29 | Tokyo, Japan | |
| 10–2 | Win | Brian Foster | Submission (Arm Triangle Choke) | GCM: D.O.G. 1 | 2005-03-12 | 3 | 2:53 | Tokyo, Japan | |
| 9–2 | Win | Eiji Ishikawa | Decision (Unanimous) | Pancrase: Brave 9 | 2004-10-12 | 3 | 5:00 | Tokyo, Japan | |
| 8–2 | Loss | Falaniko Vitale | Decision (Split) | SuperBrawl 36 | 2004-06-18 | 3 | 5:00 | Honolulu, Hawaii, United States | |
| 8–1 | Win | Ryuta Sakurai | Decision (Unanimous) | Pride Bushido 2 | 2004-02-15 | 2 | 5:00 | Yokohama, Japan | |
| 7–1 | Win | Kousei Kubota | TKO (Punches) | GCM: Demolition 13 | 2004-01-18 | 1 | 1:47 | Japan | |
| 6–1 | Loss | Amar Suloev | TKO (Punches) | M-1 MFC: Russia vs. the World | 2003-10-10 | 1 | 4:44 | Moscow, Russia | |
| 6–0 | Win | Kazuhiro Hanada | TKO (Strikes) | GCM: Demolition 9 | 2003-07-21 | 1 | 4:47 | Yokohama, Japan | |
| 5–0 | Win | Hidehiko Hasegawa | Decision (Unanimous) | GCM: Demolition 7 | 2003-05-01 | 2 | 5:00 | Tokyo, Japan | |
| 4–0 | Win | Hikaru Sato | Decision (Unanimous) | Pancrase: Hybrid 1 | 2003-01-26 | 2 | 5:00 | Tokyo, Japan | |
| 3–0 | Win | Sen Nakadai | Decision (Unanimous) | Pancrase: Spirit 8 | 2002-11-30 | 2 | 5:00 | Yokohama, Japan | |
| 2–0 | Win | Steve White | Submission (Strikes) | Pride The Best Vol.3 | 2002-10-20 | 2 | 3:25 | Tokyo, Japan | |
| 1–0 | Win | Kyosuke Sasaki | Decision (Unanimous) | GCM: Demolition 1 | 2002-09-08 | 2 | 5:00 | Japan | |
