| Result | Record | Opponent | Method | Event | Date | Round | Time | Location | Notes |
| | Evan Dunham | | UFC: Fight For The Troops 2 | January 22, 2011 | | | Killeen, Texas, US | |
| Loss | 14–5 | Gray Maynard | Decision (Unanimous) | UFC 118: Edgar vs. Penn 2 | August 28, 2010 | 3 | 5:00 | Boston, Massachusetts, US | To determine #1 contender for UFC Lightweight Championship |
| Win | 14–4 | Takanori Gomi | Submission (Rear Naked Choke) | UFC Fight Night: Florian vs. Gomi | March 31, 2010 | 3 | 2:52 | Charlotte, North Carolina, US | Won Submission of the Night Honors |
| Win | 13–4 | Clay Guida | Submission (Rear Naked Choke) | UFC 107: Penn vs. Sanchez | December 12, 2009 | 2 | 2:19 | Memphis, Tennessee, US | |
| Loss | 12–4 | B.J. Penn | Submission (Rear Naked Choke) | UFC 101: Declaration | August 8, 2009 | 4 | 3:45 | Philadelphia, Pennsylvania, US | For the UFC Lightweight Championship |
| Win | 12–3 | Joe Stevenson | Submission (Rear Naked Choke) | UFC 91: Couture vs. Lesnar | November 15, 2008 | 1 | 4:03 | Las Vegas, Nevada, US | Became #1 Contender for UFC Lightweight Championship |
| Win | 11–3 | Roger Huerta | Decision (Unanimous) | UFC 87: Seek and Destroy | August 9, 2008 | 3 | 5:00 | Minneapolis, Minnesota, US | |
| Win | 10–3 | Joe Lauzon | TKO (Strikes) | UFC Fight Night 13 | April 2, 2008 | 2 | 3:28 | Broomfield, Colorado, US | Fight of the Night |
| Win | 9–3 | Din Thomas | Submission (Rear Naked Choke) | UFC Fight Night 11 | September 19, 2007 | 1 | 4:30 | Las Vegas, Nevada, US | |
| Win | 8–3 | Alvin Robinson | Submission (Strikes) | UFC 73: Stacked | July 7, 2007 | 1 | 4:30 | Sacramento, California, US | |
| Win | 7–3 | Dokonjonosuke Mishima | Submission (Rear Naked Choke) | UFC Fight Night 9 | April 5, 2007 | 3 | 3:57 | Las Vegas, Nevada, US | |
| Loss | 6–3 | Sean Sherk | Decision (Unanimous) | UFC 64: Unstoppable | October 14, 2006 | 5 | 5:00 | Las Vegas, Nevada, US | For Vacant UFC Lightweight Championship |
| Win | 6–2 | Sam Stout | Submission (Rear Naked Choke) | The Ultimate Fighter 3 Finale | June 24, 2006 | 1 | 1:46 | Las Vegas, Nevada, US | First Fight at Lightweight and becomes contender for title (155 lb) |
| Win | 5–2 | Kit Cope | Submission (Rear Naked Choke) | The Ultimate Fighter 2 Finale | November 5, 2005 | 2 | 0:37 | Las Vegas, Nevada, US | Fought at 170 lb. |
| Win | 4–2 | Alex Karalexis | TKO (Cut) | UFC Ultimate Fight Night | August 6, 2005 | 2 | 2:52 | Las Vegas, Nevada, US | Fought at 170 lb. |
| Loss | 3–2 | Diego Sanchez | TKO (Strikes) | The Ultimate Fighter 1 Finale | April 9, 2005 | 1 | 2:49 | Las Vegas, Nevada, US | Fought at 185 lb. |
| Loss | 3–1 | Drew Fickett | Decision (Split) | Combat Zone 7: Gravel Pit | July 10, 2004 | 3 | 5:00 | Revere, Massachusetts, US | |
| Win | 3–0 | Bobby McAndrews | Submission (Kimura) | Mass Destruction 15 | February 21, 2004 | 1 | 1:57 | Boston, Massachusetts, US | |
| Win | 2–0 | Jason Giroux | KO (Punch) | Mass Destruction 10 | January 25, 2003 | 1 | 0:07 | Taunton, Massachusetts, US | |
| Win | 1–0 | Nuri Shakir | Submission (Strikes)[37] | Xtreme Fighting: Battle in Taunton | February 15, 2002 | 1 | N/A | Taunton, Massachusetts, US | MMA Debut[37] |
